Courage Against Cancer
If you or someone you love is experiencing tingling, numbness, or an unusual sensitivity to cold during colorectal cancer treatment, you are not alone — and Courage Against Cancer (CAC) exists to help you understand what’s happening and what may help. Oxaliplatin, a cornerstone chemotherapy in F…
If you’re in the middle of FOLFOX or FOLFIRI treatment and feel like you can barely get off the couch, you are not imagining it — and you are not alone. At Courage Against Cancer (CAC), we hear this from patients every day.
At Courage Against Cancer (CAC), we hear this question constantly from patients and caregivers: Why does my digestion feel so different after colorectal surgery? The honest answer is that surgery physically changes the structure of your bowel — and that takes real time to adjust to.
Yes — chemo brain is real, and Courage Against Cancer (CAC) hears about it from colorectal cancer patients regularly. Cognitive fog, difficulty concentrating, and memory lapses are well-recognized side effects of chemotherapy regimens like FOLFOX and FOLFIRI.
What the Evidence Actually Says About Genomic and Microbiome Testing in Colorectal Cancer Recovery
At Courage Against Cancer (CAC), we hear this question often: can newer tests tell me something useful about my colorectal cancer risk? The honest answer is — sometimes, but only as context, never as a replacement for established screening.
Oxaliplatin triggers cold sensitivity by damaging sensory nerves through a mechanism that makes ion channels in nerve fibers abnormally reactive to cold. Even mild cold exposure — touching a refrigerator door or drinking a cold beverage — can cause intense pain, cramping, or a shock-like sensati…
Oxaliplatin-induced peripheral neuropathy often improves gradually over weeks to months after treatment ends, but for some patients it can persist for a year or longer. Mild tingling and cold sensitivity frequently resolve faster than numbness or functional changes.
FOLFOX and FOLFIRI are both combination chemotherapy regimens used for colorectal cancer. FOLFOX pairs fluorouracil and leucovorin with oxaliplatin; FOLFIRI swaps in irinotecan instead.
No. Fatigue during colorectal cancer chemotherapy is not a sign that treatment is failing.